Despite being an ore of lead handling clean galena poses no risk at all. Lead cannot be absorbed through the skin. Galena would be hazardous if ingested so even though this piece is clean gives off no dust, it's still good practice to wash your hands after handling it.
In Ancient Egypt galena was used to protect the eyes from the sun as well as to repel flies. It was also mixed with other ingredients to make a cosmetic known as kohl. Today in crystal healing galena is believed to be beneficial for doctors, homeopaths and herbalists due to its holistic healing properties.